Extrapharmacological Safety Topics in Psychedelic-Assisted Psychotherapy (2024)

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JAMA Psychiatry

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    May 31, 2023

    AbigailCalder,MSc1; GregorHasler,MD1

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    • 1University of Fribourg Center for Psychiatric Research, Fribourg, Switzerland

    JAMA Psychiatry. 2023;80(8):761-762. doi:10.1001/jamapsychiatry.2023.1031

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    The increasing popularity of psychedelic-assisted psychotherapy (PAP) has generated important discussions about the safety of psychedelic drugs. However, arguably the most important safety concerns arise from extrapharmacological factors. Treatment effects of these drugs notoriously depend on context, and they put patients in an unusually vulnerable state. Furthermore, the recent hyperbole surrounding psychedelic therapies has led to great expectations in both patients and therapists. These circ*mstances can make patients more vulnerable to therapist ineptitude or misconduct, as well as to disappointment due to unrealistic expectations.

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    Calder A, Hasler G. Extrapharmacological Safety Topics in Psychedelic-Assisted Psychotherapy. JAMA Psychiatry. 2023;80(8):761–762. doi:10.1001/jamapsychiatry.2023.1031

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